The Department is experienced in studying the structural and functional indices, characterizing the degree of cell damage at different stages of cryopreservation, as well as other extreme effects
Many years the main direction of the department researches is the investigation of adaptation and regeneration capabilities of cells and tissues after cold effect and also under conditions of natural and artificial anabiosis [2-3].
In the model of cultured cells there are performed the researches of the temperature effect of various range on biosynthetic processes. It has been shown that the rate of synthesis of nuclear proteins is induced by temperature factor, including cold one, and within the period of cell recovery passes ahead the rate of synthesis of total cell proteins, in this case reparative processes after hypothermia effect at cellular and organism levels have common regularities  .
At the Department a considerable attention was paid to electron microscopic investigation of crystal formation processes in the solutions of different cryoprotectants and cell suspensions. It has been shown that even in cryoprotectant presence under rapid freezing regimens there is observed non-uniform cell shrinkage and deformation of their surface by extracellular ice crystals.
For the first time in experiments there was studied the dynamics of recrystallization processes occurring