Structural Rearrangements in Cells and Their Membranes Under Long-Term Hypothermic Storage

N. V. Repin, T. P. Govorukha


Morphological investigation of ultrastructure of erythrocyte membrane and liver cells, stored for a long time under 4°C was carried-out. It was shown, that a manifested destabilisation of their membrane structure, accompanied with spiculae formation and loss of membrane material was observed following 20 days of storage. Ultrastructural state of liver cells after 1 day of storage in a liquid phase testifies to their high integrity and reversibility in the observed changes. By lability extent under hypothermic storage the intracellular structures are graded as follows: mitochondria, endoplasmic reticulum, nuclear apparatus.


erythrocytes; hepatocytes; hypothermia; ultrastructure

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