Structural Rearrangements in Cells and Their Membranes Under Long-Term Hypothermic Storage

N. V. Repin, T. P. Govorukha

Abstract


Morphological investigation of ultrastructure of erythrocyte membrane and liver cells, stored for a long time under 4°C was carried-out. It was shown, that a manifested destabilisation of their membrane structure, accompanied with spiculae formation and loss of membrane material was observed following 20 days of storage. Ultrastructural state of liver cells after 1 day of storage in a liquid phase testifies to their high integrity and reversibility in the observed changes. By lability extent under hypothermic storage the intracellular structures are graded as follows: mitochondria, endoplasmic reticulum, nuclear apparatus.


Keywords


erythrocytes; hepatocytes; hypothermia; ultrastructure

Full Text:

PDF

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

Institute for Problems of Cryobiology and Cryomedicine

23, Pereyaslavskaya str., Kharkov, Ukraine

Tel. +38057 373 4143; Fax +38057 373 5952

e-mail: journal@cryo.org.ua