Effect of Cryopreserved Placenta Extract on LPO Intensity and Lipid Hydroperoxide Content in Rat Tissue in Norm and After General Acute Cooling

Authors

  • O. S. Prokopyuk
  • A. K. Cheremskoy
  • Yu. V. Nikitchenko
  • V. V. Chizhevsky

Keywords:

spontaneous peroxidation, ascorbate-induced peroxidation, lipid hydroperoxides, cryopreserved placenta extract, general acute cooling

Abstract

Effect of cryopreserved placenta extract on lipid peroxidation (LPO) intensity and lipid hydroperoxide content in Wistar line rats’ blood serum and liver, heart homogenates under normal conditions and following general acute cooling was studied. General acute cooling of animals was found to increase the LPO intensity as well as lipid hydroperoxide content in rat liver, heart tissues and blood serum. Introduction of cryopreserved placenta extract prevents LPO activation in all studied tissues of experimental animals and we believe this testifies to the activation of biochemical adaptation mechanisms, compensating cold-caused disorders.

 

Author Biographies

O. S. Prokopyuk

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

A. K. Cheremskoy

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

Yu. V. Nikitchenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

V. V. Chizhevsky

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

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Published

2005-12-25

How to Cite

Prokopyuk, O. S., Cheremskoy, A. K., Nikitchenko, Y. V., & Chizhevsky, V. V. (2005). Effect of Cryopreserved Placenta Extract on LPO Intensity and Lipid Hydroperoxide Content in Rat Tissue in Norm and After General Acute Cooling. Problems of Cryobiology and Cryomedicine, 15(4), 681–687. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1219

Issue

Section

Cryomedicine, Clinical and Experimental Transplantology