A Comparative Study of Cooltech® Handpieces for Cryoadipolysis Using Numerical Simulation
DOI:
https://doi.org/10.15407/cryo28.04.343Keywords:
cryoadipolysis, non-invasive fat removal, apoptosis, adipocyte, non-invasive body contouring, multiphysics simulation software, cooling, computer modelling, skin barrierAbstract
Cryoadipolysis is a non-invasive procedure that results in a significant reduction of localized subcutaneous fat. The purpose of the study was to compare the cooling dynamics of Cooltech® handpieces analysing simulations of their performance and operational efficiency with Comsol Multiphysics®. All handpieces showed a timebased decreasing tendency in temperature. The central zone of all showed a similar response, except the handpiece that can lodge smaller volume of fat. The greater the volumetric capacity of fat, the less homogeneous was the temperature distribution, and the handpieces needed more time to reach the target temperatures. The widest handpiece reached a lower percentage of fat (69.06%) below the crystallization temperatures, and the handpiece that can lodge the larger volume of all tested, reached 81.93%. Numerical simulations, and particularly the model applied, are a very useful tool to optimize treatment time and improve the designs and therapeutic efficacy of handpieces.
Probl Cryobiol Cryomed 2018; 28(4): 343-356
References
Alumina ceramic (94% alumina) [SubsTech] [Internet]. [cited 2018 Jun 4]. Available from:http://www.substech.com/dokuwiki/doku.php?id=alumina_ceramic_94_alumina
COMSOL Multiphysics® Modeling Software [Internet]. [cited 2018 Sep 7]. Available from: https://www.comsol.es/
Cosmetic Surgery National Data Bank Statistics [Internet]. American Society for Aesthetic Plastic Surgery (ASAPS). 2017. 27 p. [cited 2018 Sep 7]. Available from: https://www.surgery.org/sites/default/files/ASAPS-Stats2017.pdf
Ingargiola MJ, Motakef S, Chung MT, Vasconez HC, Sasaki GH. Cryolipolysis for Fat Reduction and Body Contouring: Safety and Efficacy of Current Treatment Paradigms. Plast Reconstr Surg. 2015 Jun;135(6):1581–90.
Manstein D, Laubach H, Watanabe K, Farinelli W, Zurakowski D, Anderson RR. Selective cryolysis: A novel method of non-invasive fat removal. Lasers Surg Med. 2008 Nov;40(9):595–604.
Pham QT. Food freezing and thawing calculations. New York: Springer-Verlag; 2014. 153 p. CrossRef
Pinto H. Lipocryolysis: Cooling Speed Affects Adipocyte Survival. J Surg. 2015;3(1):11.
Pinto HR, Garcia-Cruz E, Melamed GE. A study to evaluate the action of lipocryolysis. Cryo-Letters. 2012;33(3):177–81.
Pinto H, Ricart-Jane D, Pardina E. X-ray diffraction study confirms intra-adipocitary lipid crystallization after lipocryolysis stimulus. Cryo Letters. 2013;34(6):619–23.
Raulin C, Karsai S, editors. Laser and IPL Technology in Dermatology and Aesthetic Medicine. Berlin: Springer-Verlag; 2016. 419 p. CrossRef
Rosario N, Jazmin K, Yasmeen M, Michelle B. Cool-sculpting: Optimizing Total Fat Loss During Cryolipolysis [Internet]. Ithaca (NY): College of Agriculture and Life Sciences, Cornell University; 2018 May 19; 35 p. [cited 2018 Jun 4]. Final Report: MAE/BEE 4530: Computer-Aided Engineering Group 1. Available from: https://ecommons.cornell.edu/bitstream/handle/1813/57227/Group1-%20final%20report%202.pdf?sequence=2
Sajjadi AY, Manstein D, Carp SA. Measuring Temperature Induced Phase Change Kinetics in Subcutaneous Adipose Tissues Using Near Infrared Spectroscopy, MR Imaging and Spectroscopy and OCT. Sci Rep [Internet]. 2017 Dec 19 [cited 2018 Jun 4];7(1):17786. Available from: https://www.nature.com/articles/s41598-017-18145-9 CrossRef
Scott EP, Robinson PS, Diller TE. Development of methodologies for the noninvasive the estimation of blood perfusion using a minimally invasive thermal probe. Meas Sci Technol. 1998;9(6):888–97.
Serena R. Cryolipolysis: a technique that delivers results. Aesth Med. 2017;3(2):53–6.
Thermal Properties of Plastic Materials Material Formula Coefficient of thermal expansion x10 -6 K [Internet]. [cited 2018 Jun 4]. Professional Plastics. Available from: https://www.professionalplastics.com/professionalplastics/ThermalPropertiesofPlasticMaterials.pdf
Viera-Mármol G, GarcÃa P, Villena J. Validation of Cooling and Freezing Dynamics of Cooltech® Using an Experimentally Adjusted Physical Model. SAS J Med. 2017; 3(12):343-9.
Williams LR, Leggett RW. Reference values for resting blood flow to organs of man. Clin Phys Physiol Meas. 1989 Aug;10(3):187–217.
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