Effect of Equine Erythrocyte Incubation at 49Â°C on Amphiphilic Substance Efficiency Under Hypertonic Stress Conditions
Keywords:equine erythrocytes, hypertonic hemolysis, spectrin, amphiphilic compounds
The effect of amphiphilic compounds (C10, DM, TFP) and heat preliminary treatment of equine erythrocytes (49Â°C) on cell sensitivity to hypertonic stress (4.0 M NaCl) has been investigated. All amphiphilic compounds were shown as reducing the level of hypertonic hemolysis in equine erythrocytes. Erythrocyte incubation at 49Â°C, resulting in spectrin denaturation, reduces the level of erythrocyte hypertonic damage at 37Â°C and increases it at 0Â°C. A decrease in the efficiency of all studied amphiphilic compounds is observed under the mentioned conditions.
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Copyright (c) 2020 N. M. Shpakova, N. A. Pisarenko, N. V. Orlova
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