Effect of Low Ozone Doses on Erythrocyte Hypertonic Lysis

Authors

  • I. A. Belykh Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • I. L. Volovelskaya Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. D. Zinchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

hemolysis, erythrocytes, ozone, incubation

Abstract

There was registered the dynamics of erythrocyte hemolysis in hypertonic solutions with 0.25, 0.45, 0.85, 1 and 2 M NaCl content at 4°C within 8 days when adding ozone in 0.16, 0.32 and 0.48 mg/l dose into the medium. In the media, containing ozone in 0.16 mg/l dose the erythrocyte hemolysis increased slower, than in those with similar NaCl concentrations free of ozone additives. After erythrocyte freeze-thawing in “Propandiosakharol†cryoprotective medium there was observed the hemolysis delay when introducing 0.16 mg/l ozone into the thawed cell suspension. Results are explained with modifying the erythrocyte membrane under low ozone dose effect.

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Published

2007-10-25

How to Cite

Belykh, I. A., Volovelskaya, I. L., & Zinchenko, V. D. (2007). Effect of Low Ozone Doses on Erythrocyte Hypertonic Lysis. Problems of Cryobiology and Cryomedicine, 17(3), 237–242. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/494

Issue

Section

Theoretical and Experimental Cryobiology