Experimental Substantiation for Applying Cryopreserved Preparations of Embryofetoplacental Complex in Thyroid Gland Pathology Correction. Report I. Effect of fetal thymus preparations on rabbit thyroid gland functional activity

Authors

  • N. G. Malova V.Ya. Danilevsky Institute for Problems of Endocrine Pathology of Academy of Medical Sciences of Ukraine, Kharkov
  • T. M. Yurchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. S. Bozhko V.Ya. Danilevsky Institute for Problems of Endocrine Pathology of Academy of Medical Sciences of Ukraine, Kharkov
  • I. V. Komarova V.Ya. Danilevsky Institute for Problems of Endocrine Pathology of Academy of Medical Sciences of Ukraine, Kharkov
  • D. V. Strona State Enterprise “Interdepartmental Scientific Center of Cryobiology and Cryomedicine of National Academy of Sciences, Academy of Medical Sciences and Ministry of Health Care of Ukraine’, Kharkov
  • Yu. M. Solonets V.Ya. Danilevsky Institute for Problems of Endocrine Pathology of Academy of Medical Sciences of Ukraine, Kharkov
  • V. I. Chujkova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

fetal thymus, thyroid gland, mercazolil hypothyrosis

Abstract

The xenotransplantation effect of human fetal thymus cryopreserved biopreparation on rabbit’s thyroid gland functional activity with a suppressed thyroid function (experimental mercazolil hypothyrosis) has been studied. A normalizing effect of the performed therapy on experimental animals’ thyroid system has been noted. Stimulating effect of the preparation was proved to be a two-phase: approaching to the maximum by the 2nd month after engraftment and a gradual leveling by the 4th one. A repeated engraftment of thymus tissue stimulates a thyroid function in animals, that indicates to the capability of suppressed thyroid gland for a multiple recovery of activity after fetal thymus tissue transplantation.

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Published

2007-10-25

How to Cite

Malova, N. G., Yurchenko, T. M., Bozhko, T. S., Komarova, I. V., Strona, D. V., Solonets, Y. M., & Chujkova, V. I. (2007). Experimental Substantiation for Applying Cryopreserved Preparations of Embryofetoplacental Complex in Thyroid Gland Pathology Correction. Report I. Effect of fetal thymus preparations on rabbit thyroid gland functional activity. Problems of Cryobiology and Cryomedicine, 17(3), 290–297. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/504

Issue

Vol. 17 No. 3 (2007): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 N. G. Malova, T. M. Yurchenko, T. S. Bozhko, I. V. Komarova, D. V. Strona, Yu. M. Solonets, V. I. Chujkova

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