Hypertonic Cryohemolysis of Mammalian Erythrocytes

Authors

  • N. M. Shpakova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • S. S. Ershov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

hypertonic cryohemolysis, mammalian erythrocytes

Abstract

Sensitivity of mammalian (human, bovine, equine, canine) erythrocytes to cooling from 37 down to 0°C in hypertonic saline solutions has been studied. The obtained experimental results demonstrated hypertonic cryohemolysis as typical not only for human erythrocytes but for bovine, equine, and canine cells as well. Both canine erythrocytes and human cells are maximally damaged in the medium, containing 1.2M and 1.4M NaCl for equine ones, meanwhile for bovine erythrocytes a gradual augmentation of cryohemolysis is observed with growth in medium osmolarity (up to 2.0 M NaCl).

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Published

2006-09-15

How to Cite

Shpakova, N. M., & Ershov, S. S. (2006). Hypertonic Cryohemolysis of Mammalian Erythrocytes. Problems of Cryobiology and Cryomedicine, 16(3), 286–291. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/584

Issue

Vol. 16 No. 3 (2006): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 N. M. Shpakova, S. S. Ershov

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