Influence of Hypothermic Storage Before and After Cryopreservation on Properties of Nucleated Components and Whole Human Cord Blood Plasma

Authors

  • A. A. Tsutsayeva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. Ya. Tsyganenko Kharkov State Medical University
  • I. A. Zheltyakova Kharkov State Medical University
  • E. V. Brovko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. A. Glushko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • E. D. Rozanova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

human cord blood, nucleated cells, cord blood plasma, virus-neutralising effect

Abstract

There were presented research results of hypothermic storage duration influence of whole human cord blood before and after cryopreservation on morphofunctional parameters, cryostability of its nucleated components and virus-neutralizing plasma properties. There was shown that at hypothermic storage stage, depending on its duration, non-lethal damages of nucleated cells appeared. Maximal admissible term of hypothermic storage of human cord blood makes 24 hrs before cryopreservation and not more than 2 hrs after it. At hypothermic storage stages and after cryopreservation virus-neutralizing activity of human cord blood plasma does not statistically and significantly change.

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Published

2006-03-31

How to Cite

Tsutsayeva, A. A., Tsyganenko, A. Y., Zheltyakova, I. A., Brovko, E. V., Glushko, T. A., & Rozanova, E. D. (2006). Influence of Hypothermic Storage Before and After Cryopreservation on Properties of Nucleated Components and Whole Human Cord Blood Plasma. Problems of Cryobiology and Cryomedicine, 16(1), 45–55. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/615

Issue

Vol. 16 No. 1 (2006): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 A. A. Tsutsayeva, A. Ya. Tsyganenko, I. A. Zheltyakova, E. V. Brovko, T. A. Glushko, E. D. Rozanova

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