Effect of Alkyldimethylammonium Propansulphonates on Erythrocyte Hypertonic Hemolysis

Authors

  • N. V. Orlova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • N. M. Shpakova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

erythrocyte, hypertonic stress, alkyldimethylammonium propane sulfonates, effective concentrations, antihaemolytic activity

Abstract

The authors investigated the effect of alkyldimethylammonium propanesulfonates with the alkyl chain length of 10 (C10) and 16 (C16) carbon atoms on the erythrocytes susceptibility to the hypertonic stress (4.0 M NaCl). C10 was noted to manifest a high antihaemolytic (AH) activity under erythrocyte hypertonic stress at both 37 and 0°C. The AH values of C16 activity depend on the temperature: at 37°C the substance protects the cells from hypertonic haemolysis, but at 0°C it does not show a significant AH activity.

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Published

2004-06-15

How to Cite

Orlova, N. V., & Shpakova, N. M. (2004). Effect of Alkyldimethylammonium Propansulphonates on Erythrocyte Hypertonic Hemolysis. Problems of Cryobiology and Cryomedicine, (2), 11–16. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/683

Issue

Section

Theoretical and Experimental Cryobiology