Heterozide Derivatives as Effective Additives to Cryoprotective Media

Authors

  • V. I. Kabachny National Pharmaceutical University, Kharkov
  • N. I. Gorbunova National Pharmaceutical University, Kharkov

Keywords:

heterosides, methylxanthines, spermatozoa, succinate-, malate- and lactate dehydrogenase, fructose, hypothermia, cryopreservation

Abstract

We have investigated the effect of heteroside derivatives on succinate dehydrogenase (SDG), malate dehydrogenase (MDG), lactate dehydrogenase (LDG) activity and dynamics of fructose synthesis and uptake in bovine spermatozoa under normo-, hypothermia and cryopreservation conditions. The data obtained testify to the fact, that heteroside cryoprotective effect is stipulated by the activation of energy-producing enzymes. In addition, heterosides recover the activity of enzymes, damaged during cooling.

Published

2004-06-15

How to Cite

Kabachny, V. I., & Gorbunova, N. I. (2004). Heterozide Derivatives as Effective Additives to Cryoprotective Media. Problems of Cryobiology and Cryomedicine, (2), 28-35. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/685

Issue

Section

Theoretical and Experimental Cryobiology