Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Authors

  • T. P. Sereda Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • S. N. Lezhanin Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. A. Koptelov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. A. Bondarenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

hepatocyte, pH, osmolarity

Abstract

The influence of the media with different cation and anion composition on rat’s isolated hepatocyte resistance to the hyperosmotic stress effect under different pH medium was studied. It was demonstrated that a damaging effect increased in K+ - Na+ - Li+ cation series; CH3COO- – Cl- – NO3- anion series. A pH decrease results in the augmentation of cell resistance in all observed media, a pH increase, in contrast, reduces the cell resistance to hyperosmotic stress. A temperature decrease levels the effects of both ion medium composition and alkaline pH.

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Published

2004-03-15

How to Cite

Sereda, T. P., Lezhanin, S. N., Koptelov, V. A., & Bondarenko, V. A. (2004). Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov. Problems of Cryobiology and Cryomedicine, (1), 20–25. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/699

Issue

No. 1 (2004): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 T. P. Sereda, S. N. Lezhanin, V. A. Koptelov, V. A. Bondarenko

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