Applications of Cord Blood Cells in Neurology

Authors

  • Viktoria S. Aidarova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Olga V. Kudokotseva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Ivan I. Lomakin Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Georgiy A. Babijchuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

DOI:

https://doi.org/10.15407/cryo26.02.103

Keywords:

cell therapy, cord blood, stem cells, neurological deficit

Abstract

This review represents the findings, reflecting the main achievements in the scope of cell based therapy of nervous diseases and therapeutic potential of cord blood cells in experimental and clinical neurology. The cord blood-derived cell populations are classified and the possibility of their application in therapy of neurological deficit is demonstrated. Different approaches to cord blood cell transplantation are considered, depending on administration way and cell concentration. Possible mechanisms of therapeutic effect of these cells, as well as their ability to migrate into the brain through the blood-brain barrier are discussed.

 

Probl Cryobiol Cryomed 2016; 26(2):103-115.

Author Biographies

Viktoria S. Aidarova, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryophysiology

Olga V. Kudokotseva, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryophysiology

Ivan I. Lomakin, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryophysiology

Georgiy A. Babijchuk, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryophysiology

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Published

2015-06-23

How to Cite

Aidarova, V. S., Kudokotseva, O. V., Lomakin, I. I., & Babijchuk, G. A. (2015). Applications of Cord Blood Cells in Neurology. Problems of Cryobiology and Cryomedicine, 26(2), 103–115. https://doi.org/10.15407/cryo26.02.103