Effect of Respiration and Vascular Tone on Heart Rate Variability in Rats
Keywords:heart rate variability, spectral analysis, respiration, vascular tone, rats
Basing on findings of a combined study (electrocardiography, pneumotachography, direct sphygmography) the paper discusses the effect of respiration and vascular tone on heart rate variability (HRV) in rats and presents a physiological interpretation of the selected spectral ranges. Studying the HRV in conscious rats showed the lower HF-wave range limit to be not higher than 0.8Â Hz, and the upper one not less than 2.5 Hz;Â under stress this index increased up to 3 Hz. The experiments showed that conscious rats were characterized with the â€˜package-likeâ€™ respiration (from 2 to 15â€“20 s). The respiratory rate in each â€˜packageâ€™ was different, therefore two or more peaks might be recorded at high-frequency spectral range. This fact confirmed the existence of several oscillators-pacemakers of respiratory center. In the anaesthetised rats the vasomotor waves were established to affect the variability of respiratory and heart rates within the range of 0.25â€“0.5 Hz with 0.4 Hz peak. Therefore the lower limit of the average MF waves should not exceed 0.25 Hz.
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