Deuterium Effect on Proliferation and Clonogenic Potential of Human Dermal Fibroblasts In Vitro

Authors

  • Olena V. Zlatska
  • Dmytro O. Zubov
  • Roman G. Vasyliev
  • Anton V. Syroeshkin
  • Ihor A. Zlatskiy

DOI:

https://doi.org/10.15407/cryo28.01.049

Keywords:

water isotopic composition, deuterium depleted water, human dermal fibroblasts, proliferative potential, colonyforming ability

Abstract

Probl Cryobiol Cryomed 2018; 28(1): 049–053

Author Biographies

Olena V. Zlatska

State Institute of Genetic and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine, Kiev, Ukraine

Biotechnological Laboratory ilaya regeneration, Medical Company ilaya®, Kiev, Ukraine

Dmytro O. Zubov

State Institute of Genetic and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine, Kiev, Ukraine

Biotechnological Laboratory ilaya regeneration, Medical Company ilaya®, Kiev, Ukraine

Roman G. Vasyliev

State Institute of Genetic and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine, Kiev, Ukraine

Biotechnological Laboratory ilaya regeneration, Medical Company ilaya®, Kiev, Ukraine

Anton V. Syroeshkin

RUDN University, Moscow, Russia

Ihor A. Zlatskiy

RUDN University, Moscow, Russia

A.V. Dumansky Institute of Colloid Chemistry and Water Chemistry of the National Academy of Sciences of Ukraine, Kiev, Ukraine

References

Boros L.G., D'Agostino D.P., Katz H.E. et al. Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle. Med Hypotheses 2016; 87: 69–74. CrossRef PubMed

Doina P.M., Olariu L., Cuna S. et al. Bulletin UASVM, Veterinary Medicine 2008; 65(1): 1843.

Goncharuk V.V. Science about water. Kyiv: Nauk Dumka; 2010.

Goncharuk V.V., Kavitskaya A.A., Romanyukina I.Yu., Loboda O.A. Revealing water's secrets: deuterium depleted water. Chemistry Central Journal 2013; 7: 103–107. CrossRef PubMed

Goncharuk V.V., Syroeshkin A.V., Zlatskiy I.A. et al. Quasichemical description of the kinetics of cell death Spirostomum ambiguum biosensor for biological activity of aqueous solutions. Journal of Water Chemistry and Technology 2017; 39(2): 97–102. CrossRef

Hang M., Huynh V., Meyer T.J. Colossal kinetic isotope effects in proton-coupled electron transfer. PNAS 2004; 101(36): 13138–13141. CrossRef PubMed

Ignatov I., Mosin O.V. Isotopic composition of water and its temperature in process of evolutionary origin of life and living matter. Naukovedenie 2013; 14 (1): 1–16.

Pomytkin I.A., Kolesova O.E. Relationship between natural concentration of heavy water isotopologs and rate of H2O2 generation by mitochondria. Bull Exp Biol Med 2006; 142(5); 570–572. CrossRef PubMed

Robins R.J., Remaud G.S., Billault I. Natural mechanisms by which deuterium depletion occurs in specific positions in metabolites. European Chemical Bulletin 2012; 1(1): 39–40.

Turov V.V., Goncharuk V.V., Ogenko V.M. et al. The isotope effect in formation of surface water clusters in heterogeneous systems. Journal of Water Chemistry and Technology 2015; 37: 211–218. CrossRef

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Published

2018-03-25

How to Cite

Zlatska, O. V., Zubov, D. O., Vasyliev, R. G., Syroeshkin, A. V., & Zlatskiy, I. A. (2018). Deuterium Effect on Proliferation and Clonogenic Potential of Human Dermal Fibroblasts In Vitro. Problems of Cryobiology and Cryomedicine, 28(1), 49–53. https://doi.org/10.15407/cryo28.01.049

Issue

Vol. 28 No. 1 (2018): Probl Cryobiol Cryomed

Section

Stem Cell Day. Short Communications

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