Combined Effect of Low Temperatures and Low Molecular Fraction (Below 5 kDa) of Cord Blood in Recovering Processes in Cartilage Tissue

Authors

  • A. K. Gulevsky Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Ye. G. Ivanov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

cryoeffect, cord blood, cartilage, glycosaminoglycans, proteoglycans, regeneration

Abstract

The influence of cryoeffect combined with the application of low molecular cord blood fraction (CBF) (below 5 kDa) on metabolism of polysaccharide components of the matrix and proteins of cartilage connective tissue after mechanical trauma has been studied. It has been established that cryoeffect, combined with intramuscular injection of CBF significantly stimulates the accumulation of main matrix components: hexosamine, hexuronic acids, hyaluronic acid, chondroitin sulfates and heparin as well as the most important structural proteins in cartilage regenerate, thereby providing a high level of regeneration stimulation of traumatized cartilage tissue.

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Published

2009-12-23

How to Cite

Gulevsky, A. K., & Ivanov, Y. G. (2009). Combined Effect of Low Temperatures and Low Molecular Fraction (Below 5 kDa) of Cord Blood in Recovering Processes in Cartilage Tissue. Problems of Cryobiology and Cryomedicine, 19(4), 481–487. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/237

Issue

Vol. 19 No. 4 (2009): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 A. K. Gulevsky, Ye. G. Ivanov

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