Hemopoietic Stem Cells for Transplantation in Patients with Oncohematological Pathology

Authors

  • Zh. A. Misharina Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev
  • V. V. Balan Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev
  • I. A. Kryachok National Cancer Center, Kiev
  • Zh. M. Minchenko Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev
  • N. V. Belyayeva Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev
  • Yu. M. Samson Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev
  • V. G. Chuyskiy Kiev Center for Bone Marrow Transplantation, Kiev
  • Ye. Ye. Karamanesht Kiev Center for Bone Marrow Transplantation, Kiev
  • V. I. Khomenko Kiev Center for Bone Marrow Transplantation, Kiev
  • V. G. Bebeshko Scientific Center for Radiation Medicine of the Academy of Medical Sciences of Ukraine, Kiev

Keywords:

stem cells, peripheral blood, bone marrow, cord blood, transplantation

Abstract

The research performed demonstrated that the hemopoietic cells, derived from bone marrow (BM), peripheral and cord blood, were of a high proliferative potential and might be considered as the source for transplantation. The peripheral blood (PB) should be considered as the main source of stem cells for auto- and allotransplantation performance. The proposed methods for PB stem cells enrichment enable to obtain the number of stem cells with preserved functional activity, sufficient for hemopoietic stem cells transplantation. The usage of BM as a transplant is expedient only at insufficient collection of peripheral blood SCs. Cord blood is the most perspective source for further application as allo- and autotransplantats.

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Published

2008-12-22

How to Cite

Misharina, Z. A., Balan, V. V., Kryachok, I. A., Minchenko, Z. M., Belyayeva, N. V., Samson, Y. M., Chuyskiy, V. G., Karamanesht, Y. Y., Khomenko, V. I., & Bebeshko, V. G. (2008). Hemopoietic Stem Cells for Transplantation in Patients with Oncohematological Pathology. Problems of Cryobiology and Cryomedicine, 18(4), 465–467. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/354

Issue

Vol. 18 No. 4 (2008): Problems of Cryobiology

Section

Conference Papers

License

Copyright (c) 2020 Zh. A. Misharina, V. V. Balan, I. A. Kryachok, Zh. M. Minchenko, N. V. Belyayeva, Yu. M. Samson, V. G. Chuyskiy, Ye. Ye. Karamanesht, V. I. Khomenko, V. G. Bebeshko

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