Effect of Low Ozone Doses on Erythrocyte Hypertonic Lysis
Keywords:
hemolysis, erythrocytes, ozone, incubationAbstract
There was registered the dynamics of erythrocyte hemolysis in hypertonic solutions with 0.25, 0.45, 0.85, 1 and 2 M NaCl content at 4°C within 8 days when adding ozone in 0.16, 0.32 and 0.48 mg/l dose into the medium. In the media, containing ozone in 0.16 mg/l dose the erythrocyte hemolysis increased slower, than in those with similar NaCl concentrations free of ozone additives. After erythrocyte freeze-thawing in “Propandiosakharol†cryoprotective medium there was observed the hemolysis delay when introducing 0.16 mg/l ozone into the thawed cell suspension. Results are explained with modifying the erythrocyte membrane under low ozone dose effect.
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Copyright (c) 2020 I. A. Belykh, I. L. Volovelskaya, V. D. Zinchenko
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