Intravenous Injection of Embryonic Neural Cells to Rats with Chronic Alcohol Poisoning

Authors

  • A. Yu. Petrenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • G. A. Kovalev V.N. Karazin Kharkov National University, Kharkov
  • V. I. Grischenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

embryonic neural cells, cryopreservation, transplantation, intravenous injection, chronic alcohol poisoning, model, rat females, liver

Abstract

The problem of correcting the consequences of chronic alcoholic poisoning was studied. The efficiency of intravenous injection of embryonic neural cells (ENCs) to correct the consequences of chronic alcoholic poisoning even at the background of continued alcohol intake in small doses was found out. An intravenous introduction of cryopreserved human ENCs to rats was shown as causing no negative effect on intact animals. In the model of chronic alcohol poisoning the ENCs injection was demonstrated to result in the improvement of an organism’s general state and functional state of liver: it decreased the prothrombin time, hexenal sleep and increased albumin content in blood plasm.

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Published

2005-03-15

How to Cite

Petrenko, A. Y., Kovalev, G. A., & Grischenko, V. I. (2005). Intravenous Injection of Embryonic Neural Cells to Rats with Chronic Alcohol Poisoning. Problems of Cryobiology and Cryomedicine, 15(1), 71–78. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/648

Issue

Vol. 15 No. 1 (2005): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 A. Yu. Petrenko, G. A. Kovalev, V. I. Grischenko

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