Solid Carbon Dioxide Based Cryosurgical Device and Its Application for Stereotactic Brain Surgery

Authors

  • Andrey I. Kholyavin N.P. Bekhtereva Institute of Human Brain of Russian Academy of Sciences, St. Petersburg, Russia
  • Vladimir B. Nizkovolos N.P. Bekhtereva Institute of Human Brain of Russian Academy of Sciences, St. Petersburg, Russia

DOI:

https://doi.org/10.15407/cryo24.04.354

Keywords:

stereotaxis, neurosurgery, intracerebral tumors, cryosurgery, cryodestruction, Parkinson's disease, epilepsy, obsessive-compulsive disorder

Abstract

In the laboratory of stereotactic methods of IHB RAS there has been designed the cryosurgical device based on solid carbon dioxide as a cold source. This device was applied at neurosurgical clinic in stereotactic brain surgeries such as: punctate destructions of subcortical structures in therapy of epilepsy, Parkinson's disease and other chronic CNS diseases; multiposition cryodestructions of intracerebral tumours, localised in deep and functionally important brain compartments. Clinical results demonstrate the advantages of the device when exposed to brain tissue such as: the safety, controllability, easy handling, etc. As a result of cryodestruction application there was a significant increase in survival rate of patients with deep brain tumours previously considered as inoperable.


Probl Cryobiol Cryomed 2014; 24(4):354-365.

Author Biographies

Andrey I. Kholyavin, N.P. Bekhtereva Institute of Human Brain of Russian Academy of Sciences, St. Petersburg, Russia

Laboratory of Stereotaxic Methods

Vladimir B. Nizkovolos, N.P. Bekhtereva Institute of Human Brain of Russian Academy of Sciences, St. Petersburg, Russia

Laboratory of Stereotaxic Methods

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Published

2014-12-20

How to Cite

Kholyavin, A. I., & Nizkovolos, V. B. (2014). Solid Carbon Dioxide Based Cryosurgical Device and Its Application for Stereotactic Brain Surgery. Problems of Cryobiology and Cryomedicine, 24(4), 354–365. https://doi.org/10.15407/cryo24.04.354

Issue

Vol. 24 No. 4 (2014): Problems of Cryobiology and Cryomedicine

Section

Cryogenic Equipment

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Copyright (c) 2020 Andrey I. Kholyavin, Vladimir B. Nizkovolos

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