Ultrastructure of Porcine Pericardium and Aortic Valve Tissues, Devitalized with Cryogenic and Irradiation Exposures

Authors

  • Nikolay V. Repin Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Larisa N. Marchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Tatiana P. Govorukha Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Irina P. Mikhailova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Anna A. Manchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • Boris P. Sandomirsky Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

DOI:

https://doi.org/10.15407/cryo25.03.246

Keywords:

acellular xenogeneic materials, devitalization, freeze-thawing, ionizing irradiation, ultrastructure, pericardium, aortic valve

Abstract

This paper deals with morphological assessment of cryo- and radiodevitalized tissue biomaterial, i. e. pericardium and aortic valve as well as a cell-free xeno-carcass designing. Structure of the studied tissues after low temperature, ionizing and combined exposures was investigated by optical and electron microscopies. The application of this method to devitalize the pericardium and aortic valve is shown to result in the expressed destructive changes of cell elements, but the spatial location and structural integrity of connective tissue fibrous components are preserved.


Probl Cryobiol Cryomed 2015; 25(3):246-254.

Author Biographies

Nikolay V. Repin, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryomorphology

Larisa N. Marchenko, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryomorphology

Tatiana P. Govorukha, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Cryomorphology

Irina P. Mikhailova, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Experimental Cryomedicine

Anna A. Manchenko, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Experimental Cryomedicine

Boris P. Sandomirsky, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Department of Experimental Cryomedicine

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Published

2015-09-21

How to Cite

Repin, N. V., Marchenko, L. N., Govorukha, T. P., Mikhailova, I. P., Manchenko, A. A., & Sandomirsky, B. P. (2015). Ultrastructure of Porcine Pericardium and Aortic Valve Tissues, Devitalized with Cryogenic and Irradiation Exposures. Problems of Cryobiology and Cryomedicine, 25(3), 246–254. https://doi.org/10.15407/cryo25.03.246

Issue

Vol. 25 No. 3 (2015): Problems of Cryobiology and Cryomedicine

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 Nikolay V. Repin, Larisa N. Marchenko, Tatiana P. Govorukha, Irina P. Mikhailova, Anna A. Manchenko, Boris P. Sandomirsky

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