@article{Samokhina_Starodub_Babiychuk_Lomako_2012, title={Rhythmic Cold Effect on Activity of Elastases in Female Rats with Alcohol-Dependent Hypertension}, volume={22}, url={https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/97}, abstractNote={<p>Under the influence of rhythmic cold exposures (RCEs) in female rats with alcohol-dependent hypertension there was found a suppressed activity of elastases of different origin in tissues of brain cortex, lungs, heart, liver and kidneys lower than the control level. RCEs lead to oppositely directed changes in elastase-inhibitory activity (EIA) of alpha-1- proteinase inhibitor ( alpha-1-PI) caused by alcohol effect and namely to the rise in all the studied tissues except kidneys wherein there was found a decrease. Herewith if compared to the control EIA alpha-1-PI increased only in lungs and liver, <em>i. e. </em>in the sites of possible synthesis of this inhibitor. The absence of stimulating an inhibitory potential in brain cortex and heart is in accordance with local decrease of EIA alpha-1-PI in the control and may be stipulated with the fact that inhibitor does not enter from the synthesis sites.</p>}, number={1}, journal={Problems of Cryobiology and Cryomedicine}, author={Samokhina, L. M. and Starodub, N. F. and Babiychuk, G. A. and Lomako, V. V.}, year={2012}, month={Mar.}, pages={49–60} }