TY - JOUR AU - Pisarenko, N. A. AU - Shpakova, N. M. PY - 2011/01/10 Y2 - 2024/03/28 TI - Effect of Amphiphiles on Hypertonic Hemolysis of Erythrocytes, Modified with Temperature of 49°C JF - Problems of Cryobiology and Cryomedicine JA - Probl Cryobiol Cryomed VL - 20 IS - 4 SE - Theoretical and Experimental Cryobiology DO - UR - https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/169 SP - 388-395 AB - <p>The effect of thermal pre-treatment of human and bovine erythrocytes on their sensitivity to hypertonic stress (4.0 mol/l NaCl) at 37 and0°Cwas studied. It has been shown that cell incubation at49°C, causing spectrin denaturation, decreases the level of human erythrocyte hypertonic damage and does not affect the integrity of bovine erythrocytes at37°C. Hypertonic hemolysis of modified mammalian erythrocytes does not change at0°C. Cytoskeletal spectrin denaturation of bovine and human erythrocytes results in reduction of antihemolytic activity of amphiphilic substances (sodium decyl sulfate, dodecyl-β,D-maltoside, trifluoroperazine) at 37 and0°C.</p> ER -