Nitric Oxide Derivatives at Artificial Hypometabolism in Rats and Hamsters

Authors

  • A. V. Shilo Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. V. Lomako Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. N. Bondar Institute of Therapy named after L.T. Malaya of the Academy of Medical Sciences of Ukraine, Kharkov
  • G. A. Babijchuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

nitric oxide, hypometabolism, low temperature, hypoxia, hypercapnia

Abstract

The response of NO generated system of hibernator (hamster) and non-hibernator (rat) to the combination of factors (hypoxia, hypercapnia, low temperature and darkness) that promotes the development of natural hypometabolism has been studied. The combined action of increasing hypoxia and hypercapnia at the background of cooling is thought to affect the same L-arginine-NO-ways, but it does not lead to serious disturbance of NO metabolism in hibernators and non-hibernators. All discovered changes were likely adaptive and in general have been restored in 2 h and leveled in 24 h after animals arousal from the artificial hypometabolic state. The only exception is the depressed level of NOx content in hamster blood.

Downloads

Published

2005-03-22

How to Cite

Shilo, A. V., Lomako, V. V., Bondar, T. N., & Babijchuk, G. A. (2005). Nitric Oxide Derivatives at Artificial Hypometabolism in Rats and Hamsters. Problems of Cryobiology and Cryomedicine, 15(1), 3–13. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/639

Issue

Vol. 15 No. 1 (2005): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 A. V. Shilo, V. V. Lomako, T. N. Bondar, G. A. Babijchuk

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).