Effect of Xenotransplantation of Cryopreserved Organ Culture of Thyroid Gland on Physiological Parameters of Experimental Animals

Authors

  • N. A. Volkova
  • G. A. Bozhok
  • N.M. Alabedalkarim N.M. Alabedalkarim N.M.
  • Ye. I. Legach
  • T. P. Bondarenko

Keywords:

cryopreservation, thyroid gland organ culture of newborn piglets, xenotransplantation

Abstract

The functioning of native and cryopreserved organ culture of thyroid gland (OCThG) of newborn piglets at various terms after xenotransplantation in an organism of experimental animals was studied. It was shown that OCThG subjected to low temperature storage after xenotransplantation is able to synthesize and secrete thyroid hormons. It was established, that xenotransplantation of native, cryopreserved and recultured OCThG led to the increase of T3,T4 in blood plasma level in the rabbits with experimental hypothyrosis.

Author Biographies

N. A. Volkova

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

G. A. Bozhok

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

N.M. Alabedalkarim N.M. Alabedalkarim N.M.

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Ye. I. Legach

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

T. P. Bondarenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

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Published

2003-05-15

How to Cite

Volkova, N. A., Bozhok, G. A., Alabedalkarim N.M., N. A. N., Legach, Y. I., & Bondarenko, T. P. (2003). Effect of Xenotransplantation of Cryopreserved Organ Culture of Thyroid Gland on Physiological Parameters of Experimental Animals. Problems of Cryobiology and Cryomedicine, (1), 16–19. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1005

Issue

Section

Theoretical and Experimental Cryobiology