Temperature Effect on Human Erythrocyte Membrane Permeability for 1,2-Propane Diol and Dimethylsulfoxide

Authors

  • O. I. Gordiyenko

Keywords:

erythrocytes, permeability, 1, 2-propane diol, dimethylsulfoxide, Arrhenius dependencies

Abstract

The paper presents the results of study of human erythrocyte membrane permeability for 1,2-propane diol (1,2-PD) and dimethylsulfoxide (DMSO) within temperature limits of 3-37C. Arrhenius dependencies of permeability coefficients for the studied substances were shown to be underwent the series of breaks within the following temperature limits: 8-12, 18-20 and 28-30C (being known as the critical ones for some functional indices of biological membranes) with sharp changes in activation energy (EA). Some possible mechanisms of thermoinduced changes in parameters of non-electrolytes permeation via erythrocyte membrane are discussed.

Author Biography

O. I. Gordiyenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Published

2003-05-15

How to Cite

Gordiyenko, O. I. (2003). Temperature Effect on Human Erythrocyte Membrane Permeability for 1,2-Propane Diol and Dimethylsulfoxide. Problems of Cryobiology and Cryomedicine, (1), 38-45. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1008

Issue

Section

Theoretical and Experimental Cryobiology