Effect of Cryopreserved Cord Blood on Structure of Immunocompetent and Other Vital Organs at Acute Pyoperitonitis

Authors

  • K. A. Goltsev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. V. Volina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • O. Yu. Kozhina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • M. V. Ostankov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

cryopreserved human cord blood, acute pyoperitonitis, histological analysis, immunocompetent organs, liver, kidneys, lungs, intestine

Abstract

The experimental research of the effect of cryopreserved human cord blood (cHCB) introduction on the recovery of structure of immuno-competent and other vital organs of rats with acute pyoperitonitis (APP) was performed. It was shown the activation of regenerative processes under effect of cHCB in immune system organs as well as other ones (liver, kidneys, intestine and lungs) exposed to pathological changes at peritonitis development. The obtained results provide the reasons for probable cHCB administration as an immunomodulating therapy at development of acute pyoperitonitis in clinical practice.

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Published

2011-12-19

How to Cite

Goltsev, K. A., Volina, V. V., Kozhina, O. Y., & Ostankov, M. V. (2011). Effect of Cryopreserved Cord Blood on Structure of Immunocompetent and Other Vital Organs at Acute Pyoperitonitis. Problems of Cryobiology and Cryomedicine, 21(4), 429–444. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/115

Issue

Section

Cryomedicine, Clinical and Experimental Transplantology