Проблемы и перспективы использования стволовых клеток хрящевой ткани

Авторы

  • Yuri B. Chaikovsky Национальный медицинский университет имени А.А.Богомольца, г. Киев
  • Serhii B. Herashchenko Ивано-Франковский национальный медицинский университет, г. Ивано-Франковск
  • Olena I. Deltsova Ивано-Франковский национальный медицинский университет, г. Ивано-Франковск

DOI:

https://doi.org/10.15407/cryo29.04.303

Ключевые слова:

хрящевые ткани, стволовые клетки, экспериментальные модели, лабораторные животные, криоконсервирование стволовых клеток

Аннотация

Ð’ работе обÑуждаютÑÑ Ð¾Ð±Ñ‰Ð¸Ðµ вопроÑÑ‹ Ð´Ð»Ñ ÑпециалиÑтов в облаÑти биологии, криомедицины и биомеханики отноÑительно Ð¿Ñ€Ð¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ñтволовых клеток (СК) Ð´Ð»Ñ Ð»ÐµÑ‡ÐµÐ½Ð¸Ñ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹ Ñ…Ñ€Ñщевой ткани. Ð’ наÑтоÑщее Ð²Ñ€ÐµÐ¼Ñ Ð²Ñ‹Ñвлены ниши СК в гиалиновых Ñ…Ñ€Ñщах, Ñиновиальных мембранах и Ñиновиальной жидкоÑти диартрозов, межпозвоночных диÑках, и мениÑках коленных ÑуÑтавов, волокниÑÑ‚Ñ‹Ñ… Ñ…Ñ€Ñщах виÑочно-нижнечелюÑтного ÑуÑтава и ÑлаÑтичеÑких Ñ…Ñ€Ñщах ушной раковины. Определены ÑпецифичеÑкие оÑобенноÑти и механизм дейÑÑ‚Ð²Ð¸Ñ Ð¡Ðš Ñ…Ñ€Ñщевой ткани. Разработаны ÑкÑпериментальные модели патологии Ñ…Ñ€Ñщевой ткани на разных видах животных. ЭкÑпериментальные иÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ñ€Ð¾Ð´ÐµÐ¼Ð¾Ð½Ñтрировали возможноÑÑ‚ÑŒ иÑÐ¿Ð¾Ð»ÑŒÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¡Ðš Ð´Ð»Ñ Ð»ÐµÑ‡ÐµÐ½Ð¸Ñ Ð·Ð°Ð±Ð¾Ð»ÐµÐ²Ð°Ð½Ð¸Ð¹, вызванных патологией Ñ…Ñ€Ñщевой ткани. Показано, что применение криоконÑервированных СК Ñ…Ñ€Ñщевой ткани во врачебной практике ÑвлÑетÑÑ Ñффективным и перÑпективным. Ðа ÑегоднÑшний момент Ñтот Ð²Ð¾Ð¿Ñ€Ð¾Ñ Ð½ÐµÐ´Ð¾Ñтаточно иÑÑледован, поÑтому необходимо разработать оптимальные режимы замораживаниÑ, подобрать криозащитные Ñреды, а также оценить безопаÑноÑÑ‚ÑŒ такой терапии.

 

Probl Cryobiol Cryomed 2019; 29(4): XXX–XXX

Биографии авторов

Yuri B. Chaikovsky, Национальный медицинский университет имени А.А.Богомольца, г. Киев

Кафедра гиÑтологии и Ñмбриологии

Serhii B. Herashchenko, Ивано-Франковский национальный медицинский университет, г. Ивано-Франковск

Кафедра гиÑтологии, цитологии и Ñмбриологии

Olena I. Deltsova, Ивано-Франковский национальный медицинский университет, г. Ивано-Франковск

Кафедра гиÑтологии, цитологии и Ñмбриологии

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Загрузки

Опубликован

2019-12-17

Как цитировать

Chaikovsky, Y. B., Herashchenko, S. B., & Deltsova, O. I. (2019). Проблемы и перспективы использования стволовых клеток хрящевой ткани. Проблемы криобиологии и криомедицины, 29(4), 303–316. https://doi.org/10.15407/cryo29.04.303

Выпуск

Том 29 № 4 (2019): Проблемы криобиологии и криомедицины

Раздел

Обзорные статьи

Лицензия

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