Cryopreserved Chorionic Tissue in Maternal and Fetal Infection Therapy (Clinical and Experimental Research)

Authors

  • V. Yu. Prokopyuk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov Interdepartmental Scientific Center for Cryobiology and Cryomedicine of the National Academy of Sciences, Academy of Medical Sciences, Ministry of Health Care of Ukraine, Kharkov

Keywords:

cryopreservation, chorionic tissue, maternal-fetal infection

Abstract

The cryosensitivity of chorionic tissue (CT) under different cryopreservation protocols, CT effect on pregnancy proceeding and outcome in laboratory animals were investigated. The application efficiency of preparation “Platex-chorionic†(PC) in a combined therapy of maternal-fetal infection (MFI) was under study. Both DMSO and that combined with PEO-4000 were shown to be the cryoprotectants of choice for CT freezing. Chorionic tissue has no teratogenic properties and positively affects the reproductive indices. The PC use in a combined therapy of MFI enables to improve placental structure, reduce the morbidity in gestation process and labor, thereby significantly enhancing prognosis for mother and newborn.

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Published

2024-05-21

How to Cite

Prokopyuk, V. Y. (2024). Cryopreserved Chorionic Tissue in Maternal and Fetal Infection Therapy (Clinical and Experimental Research). Problems of Cryobiology and Cryomedicine, 21(3), 338–349. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/132

Issue

Vol. 21 No. 3 (2011): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 V. Yu. Prokopyuk

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