Respiratory Activity and Pro-Oxidant/Antioxidant Balance of Rat Liver after Hypothermic Storage in Presence of Bencyclane Fumarate

Authors

  • I. A. Sosimchyk Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • D. V. Cherkashina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. Yu. Somov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. Yu. Petrenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

bencyclane fumarate, liver hypothermic storage, normothermic reperfusion, respiratory parameters, peroxidation processes, antioxidant enzymes

Abstract

The influence of bencyclane fumarate on mitochondria respiratory parameters, peroxidation process intensity and antioxidant enzyme activity of rat liver after hypothermic storage and normothermic reperfusion was investigated. The uncoupling effect of bencyclane on oxidative phosphorylation processes was shown both after storage and reperfusion. Partial prevention of TBARS basal level increase and antioxidant enzyme activity decrease in liver after cold storage in the presence of1 mMof bencyclane were observed.

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Published

2010-09-20

How to Cite

Sosimchyk, I. A., Cherkashina, D. V., Somov, A. Y., & Petrenko, A. Y. (2010). Respiratory Activity and Pro-Oxidant/Antioxidant Balance of Rat Liver after Hypothermic Storage in Presence of Bencyclane Fumarate. Problems of Cryobiology and Cryomedicine, 20(3), 255–265. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/185

Issue

Vol. 20 No. 3 (2010): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 I. A. Sosimchyk, D. V. Cherkashina, A. Yu. Somov, A. Yu. Petrenko

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