Membrane Permeability of Ratâ€™s and Rabbitâ€™s Erythrocytes for Cryoprotectants of Amide and Diol Series
Keywords:cryoprotectants, membrane permeability, molecule geometric parameters, homologous series, lipid bilayer, protein channels
As a result of the performed experiments the permeability of rat and rabbit erythrocyte membranes for substances was revealed as dependent on a chemical structure, geometric parameters of molecules, physical and chemical properties of these compounds, in particular hydrophilic and hydrophobic balance of their molecules. The permeability of substances through rat erythrocyte membrane was established as higher than the rabbit one, that was stipulated by the species-specificity of these cells.
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Copyright (c) 2020 G. V. Kovalenko, I. F. Kovalenko, T. P. Linnik
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