Membrane Permeability of Rat’s and Rabbit’s Erythrocytes for Cryoprotectants of Amide and Diol Series

Authors

  • G. V. Kovalenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • I. F. Kovalenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. P. Linnik Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

cryoprotectants, membrane permeability, molecule geometric parameters, homologous series, lipid bilayer, protein channels

Abstract

As a result of the performed experiments the permeability of rat and rabbit erythrocyte membranes for substances was revealed as dependent on a chemical structure, geometric parameters of molecules, physical and chemical properties of these compounds, in particular hydrophilic and hydrophobic balance of their molecules. The permeability of substances through rat erythrocyte membrane was established as higher than the rabbit one, that was stipulated by the species-specificity of these cells.

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Published

2007-12-15

How to Cite

Kovalenko, G. V., Kovalenko, I. F., & Linnik, T. P. (2007). Membrane Permeability of Rat’s and Rabbit’s Erythrocytes for Cryoprotectants of Amide and Diol Series. Problems of Cryobiology and Cryomedicine, 17(4), 365–373. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/483

Issue

Vol. 17 No. 4 (2007): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 G. V. Kovalenko, I. F. Kovalenko, T. P. Linnik

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