Peculiarities of Isolation, Cryopreservation and Allogeneic Transplantation of Rabbit’s Hepatocytes

Authors

  • A. S. Lebedinsky
  • A. Yu. Petrenko

Keywords:

transplantation of cryopreserved hepatocytes, alanine aminotransferase, aspartate aminotransferase

Abstract

The effect of introduction rate of hepatocyte suspension into a portal vein on transaminase activity in blood and liver morphology was studied. The obtained results have demonstrated, that the rate decrease of hepatocyte introduction when transplanting into a portal vein results in an even distribution of donor’s hepatocytes to recipient’s liver, allowing to reduce the thrombogenesis in the portal blood flow system and to decrease the damage degree for recipient’s own liver. The results can be used for studying the effect of transplanted cryopreserved hepatocytes at experimental pathologies of rabbit’s liver.

Author Biographies

A. S. Lebedinsky

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

A. Yu. Petrenko

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

Downloads

Published

2003-05-15

How to Cite

Lebedinsky, A. S., & Petrenko, A. Y. (2003). Peculiarities of Isolation, Cryopreservation and Allogeneic Transplantation of Rabbit’s Hepatocytes. Problems of Cryobiology and Cryomedicine, (1), 51–58. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1010

Issue

No. 1 (2003): Problems of Cryobiology

Section

Cryopreservation of Biological Resources

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).