Liver Parenchyma Response to Subcutaneous Introduction of Thyroid and Placenta Tissue Fragments During Experimental Hypothyroidism

Authors

  • V. I. Chuykova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. N. Yurchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. M. Sharlay Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. I. Strona Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • E. P. Zhulikova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. N. Marchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. P. Govorukha Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • N. V. Repin Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. S. Kovalev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • I. I. Kondakov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

hypothyroidism, liver parenchyma, xenotransplantation, allotransplantation

Abstract

There were investigated the morphological and morphometric characteristics of rat liver parenchyma during hypothyroidism and after its correction by subcutaneous introduction of the fragments of cryopreserved xenogenic fetal thyroid gland (CXFTG), fragments of cryopreserved allogenic placenta (CAP) and their combined introduction. The modelling of medicamental hypothyroidism has been shown to be accompanied by evident liver parenchyma proteinosis. Introduction of CXFTG stimulates intracellular hepatocyte proliferation revealed in the increased binuclear hepatocyte number to the 14th day. At the same time during combined introduction of CXFTG and CAP this effect has been already observed to the 7th day after introduction.

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Published

2011-02-21

How to Cite

Chuykova, V. I., Yurchenko, T. N., Sharlay, T. M., Strona, V. I., Zhulikova, E. P., Marchenko, L. N., Govorukha, T. P., Repin, N. V., Kovalev, A. S., & Kondakov, I. I. (2011). Liver Parenchyma Response to Subcutaneous Introduction of Thyroid and Placenta Tissue Fragments During Experimental Hypothyroidism. Problems of Cryobiology and Cryomedicine, 21(1), 85–95. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/158

Issue

Vol. 21 No. 1 (2011): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 V. I. Chuykova, T. N. Yurchenko, T. M. Sharlay, V. I. Strona, E. P. Zhulikova, L. N. Marchenko, T. P. Govorukha, N. V. Repin, A. S. Kovalev, I. I. Kondakov

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