Effect of Cryopreserved Bone Marrow Transplantation on Dynamics of Recovery of Morphofunctional Properties of Lymphoid, Myeloid and Endocrine Organs in Lethally Irradiated Recipients

Authors

  • A. A. Tsutsayeva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • S. S. Chernousova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • T. A. Glushko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. E. Shatilova Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • V. V. Volina Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. V. Sokol Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. Yu. Ivakhnenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • L. G. Chernyshenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • E. V. Brovko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

lethal irradiation, transplantation, cryopreserved syngeneic bone marrow, lymphoid organs, myeloid organs, endocrine organs, hormones

Abstract

There was realised a combined study of morphofunctional properties of lymphoid, myeloid and endocrine organs in lethally irradiated mice at different stages after cryopreserved syngeneic bone marrow (CSBM) cell transplantation. The CSBM cell transplantation to lethally irradiated animals demonstrated the stimulation of recovery processes in neurohumoral organs. At the same time the wave-like changes in triiodothyronine (T3), thyroxin (T4), corticosterone and insulin hormone levels in peripheral blood, even if not reaching the level of physiological norm, provide the survival within 3 months for lethally irradiated animals, dying without transplantation to the 10th day.

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Published

2009-05-25

How to Cite

Tsutsayeva, A. A., Chernousova, S. S., Glushko, T. A., Shatilova, L. E., Volina, V. V., Sokol, L. V., Ivakhnenko, L. Y., Chernyshenko, L. G., & Brovko, E. V. (2009). Effect of Cryopreserved Bone Marrow Transplantation on Dynamics of Recovery of Morphofunctional Properties of Lymphoid, Myeloid and Endocrine Organs in Lethally Irradiated Recipients. Problems of Cryobiology and Cryomedicine, 19(1), 71–87. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/289

Issue

Vol. 19 No. 1 (2009): Problems of Cryobiology

Section

Cryomedicine, Clinical and Experimental Transplantology

License

Copyright (c) 2020 A. A. Tsutsayeva, S. S. Chernousova, T. A. Glushko, L. E. Shatilova, V. V. Volina, L. V. Sokol, L. Yu. Ivakhnenko, L. G. Chernyshenko, E. V. Brovko

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