Study of Effect of Rat Embryonic Neural Tissue Peptides on Intracerebral Tumor Cells and Functional Activity of Peripheral Blood Mononuclears

Authors

  • M. I. Lisyanyy Institute of Neurosurgery named after Acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine, Kiev
  • L. M. Belska Institute of Neurosurgery named after Acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine, Kiev
  • V. M. Semenova Institute of Neurosurgery named after Acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine, Kiev
  • V. D. Rozumenko Institute of Neurosurgery named after Acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine, Kiev
  • L. P. Stajno Institute of Neurosurgery named after Acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine, Kiev

Keywords:

peptides of embryonic brain, glioma, peripheral blood mononuclears

Abstract

The effect of embryonic brain peptides (EBP) of rats (E17) on viability of experimental cells of 101.8 strain glioma, human intracerebral tumors and functional activity of mononuclears of peripheral blood was studied. There was revealed that EBP of rats rendered a direct cytotoxic effect on cells of tumors and normalized the indices of spontaneous and stimulated production of superoxide radical of mononuclears of peripheral blood of neurooncological patients. The rate of this effect is of dose-dependent character.

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Published

2008-12-22

How to Cite

Lisyanyy, M. I., Belska, L. M., Semenova, V. M., Rozumenko, V. D., & Stajno, L. P. (2008). Study of Effect of Rat Embryonic Neural Tissue Peptides on Intracerebral Tumor Cells and Functional Activity of Peripheral Blood Mononuclears. Problems of Cryobiology and Cryomedicine, 18(4), 441–444. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/347

Issue

Vol. 18 No. 4 (2008): Problems of Cryobiology

Section

Conference Papers

License

Copyright (c) 2020 M. I. Lisyanyy, L. M. Belska, V. M. Semenova, V. D. Rozumenko, L. P. Stajno

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