Rat Liver Energetic State Under Short-Term Hypothermic Storage

Authors

  • E. N. Tkacheva Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • O. A. Semenchenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. Yu. Somov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. Yu. Petrenko Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

fetal tissue cytosol, hypothermic storage, mitochondria, respiratory substrates

Abstract

The effect of pretreatment of rats with fetal tissue cytosol on mitochondrial functional state and ATP content in isolated liver under short-term hypothermic storage has been studied. Animal pretreatment with fetal tissue cytosol was shown to result in a statistically significant increase in ATP content in an isolated liver following 1 hr of organ hypothermic storage as well as in succinatedependent respiration rate rise in V3 and V4 state according to Chance. Respiration rate in malate and glutamate presence did not differ from the control values.

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Published

2007-03-15

How to Cite

Tkacheva, E. N., Semenchenko, O. A., Somov, A. Y., & Petrenko, A. Y. (2007). Rat Liver Energetic State Under Short-Term Hypothermic Storage. Problems of Cryobiology and Cryomedicine, 17(1), 38–43. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/529

Issue

Vol. 17 No. 1 (2007): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 E. N. Tkacheva, O. A. Semenchenko, A. Yu. Somov, A. Yu. Petrenko

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