Role of Cryopreservation in Determining Component Composition and Immune Reactivity of Bone Marrow

Authors

  • I. Yu. Matsevitaya Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • M. V. Ostankov Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov
  • A. N. Goltsev Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkov

Keywords:

cryopreservation, bone marrow, immunoactivity, transplantation, GVHR

Abstract

The data, characterising GVHR development after transplantation of allogenic bone marrow, modified by component composition, are shown. Certain conditions of bone marrow cryopreservation were demonstrated as enabling to decrease a myelotransplant’s immune reactivity due to inhibiting accessory-regulatory elements function and as a result GVHR manifestation rate by increasing its protective potential.

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Published

2006-03-31

How to Cite

Matsevitaya, I. Y., Ostankov, M. V., & Goltsev, A. N. (2006). Role of Cryopreservation in Determining Component Composition and Immune Reactivity of Bone Marrow. Problems of Cryobiology and Cryomedicine, 16(1), 66–75. Retrieved from https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/618

Issue

Vol. 16 No. 1 (2006): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

License

Copyright (c) 2020 I. Yu. Matsevitaya, M. V. Ostankov, A. N. Goltsev

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