Impact of Craniocerebral Hypothermia and Cryopreserved Cord Blood on Reproductive Function of Male Rats with Chronic Alcohol Intoxication
DOI:
https://doi.org/10.15407/cryo30.04.369Ключевые слова:
chronic alcohol intoxication, rhythmic craniocerebral hypothermia, cryopreserved cord blood leukoconcentrate, reproductive function, ratsАннотация
Abstract: In this work, we have studied the impact of chronic alcohol intoxication (CAI) on reproductive function in male rats. Prolonged alcohol abuse has been shown to significantly reduce the manifestation rate of sexual activation and testosterone level in blood serum of male rats with CAI following exposure to a receptive female, as well as to change their seminal fluid composition. The rhythmic craniocerebral hypothermia (rCCH), combined with the administration of cryopreserved cord blood leukoconcentrate (cCBL) ensured to a greater extent the dynamics of functional integrity recovery of the CAI-altered reproductive system in male rats, if compared to each of these methods used solely. The authors have hypothesized the rCCH and cCBL to activate the hypothalamic-pituitary system, affecting thereby the testosterone synthesis and spermatogenesis stimulation.
Probl Cryobiol Cryomed 2020; 30(4): 369–379
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Copyright (c) 2020 Іvan І. Lomakin , Olga V. Kudokotseva , Vladyslav G. Babiichuk , Yevhenii V. Kryshtal
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