Influence of Certain Physical and Chemical Factors of Cryopreservation on Bone Marrow Cells with Various Initial Structural and Functional Status

Authors

  • Yu. A. Kozlova
  • A. N. Goltsev
  • M. V. Ostankov

Keywords:

bone marrow, autoimmune disease, osmolarity, pH

Abstract

The structural and functional organisation of bone marrow (BM) cells of the intact rats and with the experimental allergic encephalomyelitis (EAE) after the influence of physical and chemical factors, realised in the process of cryopreservation (pH and osmolarity) was estimated. The data obtained orientate to the possibility for modifying (optimising) the equilibration conditions of donor’s BM with the mentioned pathology at the stage of its preliminary preparing for freezing.

Author Biographies

Yu. A. Kozlova

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

A. N. Goltsev

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

M. V. Ostankov

Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv

 

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Published

2003-12-25

How to Cite

Kozlova, Y. A., Goltsev, A. N., & Ostankov, M. V. (2003). Influence of Certain Physical and Chemical Factors of Cryopreservation on Bone Marrow Cells with Various Initial Structural and Functional Status. Problems of Cryobiology and Cryomedicine, (4), 3–11. Retrieved from http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1072

Issue

No. 4 (2003): Problems of Cryobiology

Section

Theoretical and Experimental Cryobiology

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