The Department develops theoretical approaches and physico-mathematical theories/ models of the phenomena of transmembrane mass transfer and other processes occurring at different stages of low-temperature preservation. Such theoretical modeling was used for determination of cell membrane permeability coefficients for water molecules and cryoprotectants, determination of optimal cryopreservation regimens, etc.
• Theoretical substantiation and experimental confirmation of ways to increase the adhesion capacity of cells before and after cryopreservation by modifying the physicochemical characteristics of the substrate and the surface of cell membranes
(Research Code 188.8.131.52, State Registration Number 0111U001198). 2011-2015
• To establish the mechanisms and create a physical and mathematical theory of cell cryodamages under electrical stresses during low-temperature preservation of cell suspensions (Research Code 184.108.40.206, State Registration Number 0116U003490). 2016-2020
• Theoretical and experimental study of electrical characteristics of cell membranes at the stages of cryopreservation and their correlation with the ability of cells to adhere to flat surfaces and three-dimensional structures
(Research Code 220.127.116.11, State Registration Number 0121U108756). 2021-2025